世博娱乐

2014-09 至 2019-06，四川大学，有机化学，博士，导师：冯小明 院士

2010-09 至 2014-06，四川大学，化学，学士，导师：冯小明 院士

2019-08 至 2021-07，德克萨斯大学奥斯汀分校，合作导师：Stephen F. Martin 教授

2022年1月至今，世博娱乐官网，助理研究员

不对称氢化，氢甲酰化，二氧化碳转化

1) Mingjun Yi, Xiaoyu Wu, Jianwei Wu, Yan Lu*, Zhaoguo Zhang*, Photocatalytic α-Selective σ-Bond Hydroboration of Bicyclo[1.1.0]butanes, Org. Lett. 2026, 28, 1851-1856.

2) Limin Xu, Yuxuan Zhang, Yan Lu*, Zhaoguo Zhang*, Ru-Diphosphine catalyzed asymmetric hydrogenation of unprotected β-C-glycosidic ketones, Org. Chem. Front. 2025, 12, 6974-6979.

3) Limin Xu, Yuxuan Zhang, Yan Lu*, and Zhaoguo Zhang*, Ru-Catalyzed Asymmetric Hydrogenation of Chiral δ‑Hydroxy-β-Keto Acid Derivatives. J. Org. Chem. 2025, 90, 6903−6909.

4) Liqun Yang, Mingjun Yi, Xiaoyu Wu, Yan Lu*, and Zhaoguo Zhang*, Dirhodium(II)/XantPhos Catalyzed Synthesis of β-(E)-Vinylsilanes via Hydrosilylation and Isomerization from Alkynes,Chem. Eur. J. 2024, 30, e202402406.

5) Mingjun Yi, Xiaoyu Wu, Liqun Yang, Yao Yuan, Yan Lu*, and Zhaoguo Zhang*, Visible Light Induced B−H Bond Insertion Reaction with Diazo Compounds, J. Org. Chem. 2024, 89, 12583−12590.

6) Xiaoyu Wu, Wei Liu, Liqun Yang, Yue Wang, Tianwen Liu, Yao Yuan, Yan Lu*, and Zhaoguo Zhang*, Nickel-Catalyzed Regioselective Hydrosilylation of Conjugated Dienes, Chin. J. Chem. 2024, 42, 13−19.

7) Yan Lu, Qi Gu, Stephen F. Martin*, Structure-affinity relationships of stereoisomers of norbenzomorphan-derived σ2R/TMEM97 modulators, Eur. J. Med. Chem. 2023, 257, 115488.

8) Yuxuan Zhang, Xiaotong Li, Limin Xu, Xiaomin Xie, Yan Lu*, and Zhaoguo Zhang*, Ru-Catalyzed Enantioselective Hydrogenation of Diaryl 1,4-Diketones: Synthesis of Chiral 1,4-Diarylbutane-1,4-Diols, Org. Lett. 2022, 24, 7512−7516.

9) Yuxuan Zhang, Limin Xu, Yan Lu*, Zhaoguo Zhang*, Progress in Asymmetric Catalytic Reduction of Diketones, Chin. J. Org. Chem.2022, 42, 3221−3239.

10) Liqun Yang, Xiaoyu Wu, Wenkui Lu, Yan Lu, and Zhaoguo Zhang, Dirhodium(II)/DPPM Catalyzed 1,2-Hydrosilylation of ConjugatedDienes with Tertiary Silanes, Org. Lett. 2024, 26, 2287−2291.

11) Liqun Yang, Wenkui Lu, Xiaoyu Wu, Yan Lu, Xiaomin Xie*, and Zhaoguo Zhang*, Regio- and stereoselective hydrosilylation ofalkynes with alkoxysilanes for the synthesis of β-(Z) vinylsilanes catalyzed by a dirhodium(II)/XantPhos complex, Org. Chem. Front.2024, 11, 448–457.

12) Jing Jin,† Nicolas Arbez,† James J. Sahn,† Yan Lu,† Kathryn T. Linkens, Timothy R. Hodges, Anthony Tang, Robyn Wiseman, Stephen F. Martin*, and Christopher A. Ross*, Neuroprotective Effects of σ2R/TMEM97 Receptor Modulators in the Neuronal Model of Huntington’s Disease, ACS Chem. Neurosci. 2022, 13, 2852–2862.

13) Yan Lu, Yuhang Zhou, Jingchuan Zhang, Lili Lin*, Xiaohua Liu, and Xiaoming Feng*, Highly Regio- and Enantioselective Nitroso Diels−Alder Reaction of 1,3-Diene-1-carbamates Catalyzed by Chiral N,N′-Dioxide/Copper(II) Complex, Adv. Synth. Catal. 2018, 360, 186–191.

14) Yan Lu, Yuhang Zhou, Lili Lin*, Haifeng Zheng, Kai Fu, Xiaohua Liu, and Xiaoming Feng*, N,N′-Dioxide/Nickel(II)-Catalyzed Asymmetric Diels-Alder Reaction of Cyclopentadiene with 2,3-Dioxopyrrolidines and 2-Alkenoyl Pyridines, Chem. Commun.2016, 52, 8255–8258.

15) Yan Lu, Min Wang, Xiaohu Zhao, Xiaohua Liu*, Lili Lin, Xiaoming Feng*, Cooperative Chiral Guanidine/AgPF6 Catalyzed Asymmetric Isocyanoacetate Aldol Reaction with Isatins, Synlett2015, 26, 1545–1548.

16) Yuhang Zhou, Lili Lin, Xiaohua Liu*, Xinyue Hu, Yan Lu, Xiying Zhang, and Xiaoming Feng*, Catalytic Asymmetric Diels-Alder Reaction/[3,3] Sigmatropic Rearrangement Cascade of 1-Thiocyanatobutadienes, Angew. Chem. Int. Ed. 2018, 57, 9113–9116.

17) Jingchuan Zhang, Kai Fu, Lili Lin*, Yan Lu, Xiaohua Liu, and Xiaoming Feng*, Efficient Catalytic Enantioselective Hydroxyamination of α-Aryl-α-Cyanoacetates with 2-Nitrosopyridines, Chem. Eur. J. 2018, 24, 4289–4293.

18) Xinyue Hu, Yuhang zhou, Yan Lu, Sijia Zou, Lili Lin*, Xiaohua Liu, and Xiaoming Feng*, Catalytic Asymmetric Inverse-Electron-Demand Hetero-Diels−Alder Reaction of Dioxopyrrolidines with Hetero-Substituted Alkenes, J. Org. Chem. 2018, 83, 8679–8687.

19) Yuhang Zhou, Yan Lu, Xinyue Hu, Hongjiang Mei, Lili Lin*, Xiaohua Liu, and Xiaoming Feng*, Highly Diastereo- and Enantioselective Synthesis of Spirooxindolecyclohexaneamides through N,N′-Dioxide/Ni(II)-Catalyzed Diels-Alder Reactions, Chem. Commun. 2017, 53, 2060–2063.

20) Tengfei Kang, Shulin Ge, Lili Lin, Yan Lu, Xiaohua Liu*, Xiaoming Feng*, A Chiral N,N′-Dioxide–ZnII Complex Catalyzes the Enantioselective [2+2] Cycloaddition of Alkynoneswith Cyclic Enol Silyl Ethers, Angew. Chem. Int. Ed. 2016, 55, 5541–5544.

21) Ruixue Peng, Lili Lin*, Yuheng Zhang, Wangbin Wu, Yan Lu, Xiaohua Liu and Xiaoming Feng*, The assignment of the configuration for α-hydroxy acid esters using a CEC strategy, Org. Biomol. Chem. 2016, 14, 5258–5262.

有机化学实验