世博娱乐

2000.09-2004.06：北京大学化学与分子工程学院，学士
2004.09-2010.07：北京大学化学与分子工程学院，博士，导师：王剑波教授、张艳教授

2010.07-2012.09：日本京都大学工学院，博士后，导师：Masahiro Murakami 教授
2012.10-2016.02：德国弗莱堡大学化学系，博士后，导师：Bernhard Breit 教授
2016.03-2022.09：世博娱乐官方网站 ，长聘教轨副教授

2022.09至今           世博娱乐官方网站 ，长聘副教授

2024.01至今           世博娱乐官方网站 ，研究员

(1) 金属有机化学
(2) 不对称催化
(3) 有机合成

(21) Regio- and Enantioselective Allylic Cyanomethylation by Synergistic Rhodium and Silane Catalysis

Minghe Sun, Linsheng Wei, Changkun Li

J. Am. Chem. Soc. 2023, 145,  DOI: 10.1021/jacs.3c00244

(20) Rhodium-Catalyzed N-Reverse Prenylation of Nonactivated Indoles.

Minghe Sun,# Linsheng Wei,# Changkun Li

Synlett 2023, 34, DOI: 10.1055/a-1995-5791.

(19)  Cobalt-catalyzed regiodivergent hydrofunctionalization of allenes.

Jia-Feng Chen, Sajid Ur Rehman, Changkun Li

Org. Chem. Front., 2022,9, 6869-6874.

(18)  Rhodium-Catalyzed Regio- and Enantioselective Direct Allylation of Methyl Ketones

Bing Li, Changkun Li

Synlett 2022, 33, 1863-1867.

(17) Rh-Catalyzed Regio- and Enantioselective Allylic Phosphinylation

Bing Li, Min Liu, Sajid Ur Rehman, and Changkun Li*

J. Am. Chem. Soc. 2022, 144,  2893-2898.

(16)  Eantioselective Synthesis of Pyridiens with All-Carbon Quaternary Carbon Centers via Cobalt-Catalyzed Desymmetric

[2+2+2] Cycloaddition

Ke Li, Linsheng Wei, Minghe Sun, Bing Li, Min Liu, Changkun Li* 

Angew. Chem. Int. Ed. 2021, 60, 20204-20209.

(15)  Rhodium-Catalyzed Regio- and Enantioselective Allylic Amination of racemic 1,2-Disubstituted Allylic Phosphates.

Wen-Bin Xu,† Minghe Sun,† Mouhai Shu, Changkun Li* (†, equal contribution)

J. Am. Chem. Soc. 2021, 143, 8255-8260.

(14)  Rh-Catalyzed Chemodivergent Regio- and Enantioselective Allylic Alkylation of Indoles
Minghe Sun, Min Liu, Changkun Li*

Chem. Eur. J. 2021, 27, 3457-3462.

(13) Enantioselective Synthesis of 3-Allylindolizines via Sequential Rh-Catalyzed Asymmetric Allylation and Tschitschibabin Reaction
Ke Li, Changkun Li*

Org. Lett. 2020, 22, 9456-9461.

(12) Regio- and Enantioselective Allylic Alkylation of Terminal Alkynes by Synergistic Rh/Cu Catalysis

Wen-Yu Huang, Chun-Hua Lu, Samir Ghorai, Bing Li, Changkun Li*

J. Am. Chem. Soc. 2020, 142, 15276-15281. 

(11) Desymmetrization construction of chiral lactones by synergistic Cu(II) complex and organic base

Murad Ali, Changkun Li*

Tetrahedron Lett. 2020, //doi.org/10.1016/j.tetlet.2020.152106

(10) Cobalt/Bisoxazolinephosphine-Catalyzed Asymmetric Alkynylation of Isatins

Jia-Feng Chen, Changkun Li*

Org. Lett. 2020, 22, 4686–4691

(9) Rh(I)-Catalyzed Regio- and Enantioselective Allylic Alkylation of Meldrum's Acid 

Min Liu, Haiying Zhao,* Changkun Li.*

Chin. Chem. Lett. 2021, 32, 385-388.

(8) Cobalt-Catalyzed Regio- and Enantioselective Allylic Alkylation of Malononitriles

Samir Ghorai, Sajid Ur Rehman, Wen-Bin Xu, Wen-Yu Huang, Changkun Li.*

Org. Lett. 2020, 22, 3519-3523.

(7) Rh(I)/Bisoxazolinephosphine-Catalyzed Regio- and Enantioselective Allylic Substitutions

Wen-Bin Xu, Samir Ghorai, Wenyu Huang, Changkun Li.*

ACS. Catal. 2020, 10, 4491-4496. 

(6)  Pd-Catalyzed Enantioselective Synthesis of 2-Methyl-3-methyleneindoline. 

Chun-Hua Lu, Sima, Darvishi, Vahid, Khakyzadeh, Changkun Li.*

Chin. Chem. Lett. 2020, 31, doi.org/10.1016/j.cclet.2020.02.056. 

(5) Cobalt-Catalyzed gem-Cross-Dimerization of Terminal Alkynes.

Jia-Feng Chen, Changkun Li.*

ACS. Catal. 2020, 10, 3881-3889. 

(4) Cobalt-Catalyzed Regio- and Enantioselective Allylic Amination.

Samir Ghorai, Sahadev Shrihari Chirke, Wen-Bin Xu, Jia-Feng Chen, Changkun Li.*

J. Am. Chem. Soc. 2019, 141, 11430−11434.

(3) Construction of Vicinal Quaternary Carbon Centers via Cobalt-Catalyzed  Asymmetric Reverse Prenylation.

Minghe Sun#, Jia-Feng Chen#, Shufeng Chen, Changkun Li.*

Org. Lett. 2019, 21, 1278-1281. (#, equal contribution)

(2) Enol Ester Synthesis via Cobalt-Catalyzed Regio- and Stereoselective

Addition of Carboxylic Acids to Alkynes.

Jia-Feng Chen, Changkun Li.*

Org. Lett. 2018, 20, 6719-6724.

(1)  Rh(I)-Catalyzed Carbonylative [3+1] Constrcution of Cyclobutenones

via C-C s-Bond Activation of Cyclopropenes.

Wen-Bin Xu, Changkun Li,* and Jianbo Wang

Chem. Eur. J. 2018, 24, 15786-15790.

2016年之前：

(1) Rhodium-Catalyzed Chemo-, Regio-, and Enantioselective Addition of 2-Pyridones to Terminal Allenes
Changkun Li, Matthias Kähny and Bernhard Breit* Angew. Chem., Int. Ed. 2014, 53, 13780-13784.
(2) Rhodium-Catalyzed Chemo- and Regioselective Decarboxylative Addition of β-Ketoacids to Allenes: Efficient Construction of Tertiary and Quaternary Carbon Centers.
Changkun Li, and Bernhard Breit* J. Am. Chem. Soc. 2014, 136, 862-865.
(3) Pyridine-Directed Palladium-Catalyzed Phosphonation of C(sp2)-H Bonds
Changkun Li, Takaaki Yano, Naoki Ishida, and Masahiro Murakami* Angew. Chem., Int. Ed. 2013, 52, 9801-9804.
(4) Gold(I)-Catalyzed Cycloisomerization of Enynes Containing Cyclopropenes
Changkun Li, Yi Zeng, Hang Zhang, Jiajie Feng, Yan Zhang, Jianbo Wang* Angew. Chem., Int. Ed. 2010, 49, 6413-6417.

2020 Thieme Chemistry Journal Award

2016 入选中组部国家高层次海外人才计划青年项目

2013 德国洪堡基金会奖学金
2011 日本学术振兴会（JSPS）奖学金