世博娱乐

2011.09~2015.10    博士    应用化学                 上海交通大学（导师: 张万斌 教授）

2008.09~2011.07    硕士    制药工程与技术     华东理工大学（导师: 曾步兵 教授）

2004.09~2008.07    学士    制药工程与技术     贵州大学

2020.05~至今         长聘（教轨）副教授       上海交通大学

2017.04~2019.07    博士后                               美国犹他大学（合作导师: Prof. Matthew S. Sigman）

2015.11~2020.04    师资博士后                       上海交通大学（合作导师: 颜德岳 院士 和 张万斌 教授）

不饱和双键（烯烃和酮）高值转化

重大需求药物或关键中间体的高效绿色制备

Haipeng Wei, Yicong Luo, Jinbao Ren, Qianjia Yuan*, and Wanbin Zhang*. Ni(II)-Catalyzed Asymmetric Alkenylation and Arylation of Aryl Ketones with Organoborons via 1,5-Metalate Shift. Nat. Commun. 2024, 15,  8775.

Zhengdong Ding, Yicong Luo, Qianjia Yuan, Guangjie Wang, Zhenpeng Yu, Min Zhao, Delong Liu, and Wanbin Zhang*. Ru-Catalyzed Asymmetric Hydrogenation of α,β-Unsaturated γ-Lactams. J. Am. Chem. Soc. 2024, 146, 25312-25320.（应用于抗癫痫药物--布瓦西坦制备工艺）

Tierui Pan, Qianjia Yuan*, Defeng Xu*, and Wanbin Zhang*. Iridium-Catalyzed Asymmetric Hydrogenation of Unfunctionalized Cycloalkenes to Access Chiral 2-Aryl Tetralins.  Org. Lett. 2024, 26, 5850-5855. （应用于治疗晚期乳腺癌药物--艾拉司群制备工艺）

Mo Wang, Lu Zhang, Xiaohong Huo, Zhenfeng Zhang, Qianjia Yuan, Panpan Li, Jianzhong Chen, Yashi Zou, Zhengxing Wu, and Wanbin Zhang*. Catalytic Asymmetric Synthesis of the Anti-COVID-19 Drug Remdesivir.  Angew. Chem. Int. Ed. 2020, 59, 20814-20819. (VIP)（应用于抗新冠药物--瑞德西韦制备工艺）

Fei Li, Yicong Luo, Jinbao Ren, Qianjia Yuan*, Deyue Yan, and Wanbin Zhang*. Iridium-Catalyzed Remote Site-Switchable Hydroarylation of Alkenes Controlled by Ligands. Angew. Chem. Int. Ed. 2023, 62, e202309859. (Hot Paper)

Tao Song, Yicong Luo, Kuiyang Wang, Bingyi Wang, Qianjia Yuan*, and Wanbin Zhang*. Nickel-Catalyzed Remote C(sp³)-N/O Bond Formation of Alkenes with Unactivated Amines and Alcohols. ACS Catal. 2023, 13, 4409-4420.

Qianjia Yuan, and Matthew S. Sigman*. Palladium-Catalyzed Enantioselective Relay Heck Arylation of Enelactams: Accessing α,β-Unsaturated δ-Lactams. J. Am. Chem. Soc. 2018, 140, 6527-6530.

Jianbo Liu, Qianjia Yuan, F. Dean Toste, and Matthew S. Sigman*. Enantioselective Construction of Remote Tertiary Carbon-Fluorine Bonds. Nat. Chem. 2019, 11, 710-715.

Fei Li, Yicong Luo, Jinbao Ren, Qianjia Yuan*, Deyue Yan, and Wanbin Zhang*. Iridium-Catalyzed Asymmetric Hydroarylation of Unactivated Alkenes with Heterobiaryls: Simultaneous Construction of Axial and Central Chirality. Org. Lett. 2024, 26, 6835-6840.

Fei Li, Jinbao Ren, Yifan Song, Qianjia Yuan*, Deyue Yan, and Wanbin Zhang*. Iridium-Catalyzed 1,3-Rearrangement of Allylic Ethers. Org. Lett. 2023, 25, 8727–8732.

Tao Song, Kuiyang Wang, Qianjia Yuan*, and Wanbin Zhang*. Nickel-Catalyzed Hydroamination and Hydroalkoxylation of Enelactams with Unactivated Amines and Alcohols.  Org. Lett. 2023, 25, 6093-6098.

Yu Nie^#, Qianjia Yuan^#, and Wanbin Zhang*. Axis-Unfixed Biphenylphosphine-Oxazoline Ligands: Design and Applications in Asymmetric Catalytic Reactions. Chem. Rec. 2023, 23, e202300133. (Invited Account; ^#co-first author)

 Zhengdong Ding, Feng Gao, Yining Lu, Qianjia Yuan*, Wei-Ping Deng*, and Wanbin Zhang*. Asymmetric Hydrogenation of Tetrasubstituted α,β-Unsaturated Ketones: Access to Chiral 2-Substituted Cyclopentyl Aryl Ketones. Precis. Chem. 2023, 1, 146-152. (Invited paper)

Fei Li, Yicong Luo, Xuejie Zhu, Yong Ye, Qianjia Yuan*, and Wanbin Zhang*. Iridium-Catalyzed 1,3-Rearrangement of Allylic Alcohols. Chem. Eur. J. 2023, 29, e202300027.

Yu Nie, Jing Li, Qianjia Yuan*, and Wanbin Zhang*. Synthesis of Chiral Hydantoins and Thiazolidinediones via Iridium-Catalyzed Asymmetric Hydrogenation. Chin. J. Chem. 2022, 40, 819-824.

Yu Nie, Qianjia Yuan, Feng Gao, Masahiro Terada, and Wanbin Zhang*. Iridium-Catalyzed Double Asymmetric Hydrogenation of 2,5-Dialkylienecyclopentanones for the Synthesis of Chiral Cyclopentanones.  Org. Lett. 2022, 24, 7878-7882.

Yu Nie, Jing Li, Jun Yan, Qianjia Yuan*, and Wanbin Zhang*. Synthesis of Chiral 2-Substituted 1,4-Benzoxazin-3-ones via Iridium-Catalyzed Enantioselective Hydrogenation of Benzoxazinones. Org. Lett. 2021, 23, 5373-5377.

Chenghao Ye, Feng Gao, Haipeng Wei, Jianzhong Chen, Guoqiang Yang, Qianjia Yuan*, and Wanbin Zhang*. Pd(II)-Catalyzed Enantioselective Ring-Contraction for the Construction of 1,4-Benzoxazines. J. Org. Chem. 2021, 86, 16573-16581.

Qianjia Yuan^#, Matthew B. Prater^#, and Matthew S. Sigman*. Enantioselective Synthesis of γ-Functionalized Cyclopentenones and δ-Functionalized Cycloheptenones Utilizing a Redox-Relay Heck Strategy. Adv. Synth. Catal. 2020, 362, 326-330. (Special issue honoring Eric Jacobsen on his 60th birthday). (^#co-first author)

Qianjia Yuan, and Matthew S. Sigman*. Palladium-Catalyzed Enantioselective Alkenylation of Enelactams using a Relay Heck Strategy. Chem. Eur. J. 2019, 25, 10823-10827.

Nicholas J. Race^#, Qianjia Yuan^#, and Matthew S. Sigman*. Enantioselective C2-Alkylation of Indoles through a Redox-Relay Heck Reaction of 2-Indole Triflates. Chem. Eur. J. 2019, 25, 512-515. (^#co-first author)

Kun Yao, Qianjia Yuan, Xingxin Qu, Yangang Liu, Delong Liu*, and Wanbin Zhang*. Pd-Catalyzed Asymmetric Allylic Substitution Cascade Using α-(Pyrdin-1-yl)-acetamides Formed in situ as Nucleophiles. Chem. Sci. 2019, 10, 1767-1772. 

Qianjia Yuan, Delong Liu*, and Wanbin Zhang*. Synthesis of Chiral γ-Lactams via in Situ Elimination/Iridium-Catalyzed Asymmetric Hydrogenation of Racemic γ-Hydroxy γ-Lactams. Org. Lett. 2017, 19, 1886-1889. 

Qianjia Yuan, Delong Liu*, and Wanbin Zhang*. Iridium-Catalyzed Asymmetric Hydrogenation of β,γ-Unsaturated γ-Lactams: Scope and Mechanistic Studies. Org. Lett. 2017, 19, 1144-1147.

Qianjia Yuan, and Wanbin Zhang*. Applications of Phosphoramidite Ligands in Ir-Catalyzed Asymmetric Hydrogenation Reactions. Chin. J. Org. Chem. 2016, 36, 274-282.

Qianjia Yuan, Kun Yao, Delong Liu, and Wanbin Zhang*. Iridium-Catalyzed Allyl-Allyl Cross-Coupling of Allylic Carbonates with (E)-1,3-Diarylpropenes. Chem. Commun. 2015, 51, 11834-11836.

CN201210181561.7；CN201310100684.8；CN201310098445.3；CN201310100682.9；CN201310100681.4；CN201310100675.9；WO2013181913；CN102199186B；CN102295679B；CN101973905A；CN117362142A；CN202010495819；CN202010495820；CN116603570A；PCT/CN2023/082161；CN202210736574.X；CN202210736573.5.

国家自然科学奖二等奖（5/5）

"青蒿素的高效合成" 入选2012年国内十大科技新闻

"青蒿素的高效合成" 入选2012年上海市十大科技成果

上海市产学研合作优秀项目奖特等奖（2/10）

上海市浦江（A类）人才计划

上海市普通高等学校优秀毕业生

博士研究生国家奖学金

研究生：《高等有机化学》
本科生：《有机化学》《有机化学实验》