世博娱乐

2013-2016 中国科学院上海应用物理研究所 博士
2010-2013 中国科学院上海应用物理研究所 硕士
2006-2010 合肥工业大学 学士

2021.08-至今         世博娱乐官方网站 ，长聘教轨副教授

2018.10-2021.07，世博娱乐官方网站 ，长聘教轨助理教授
2016.9-2018.9，华南理工大学发光材料与器件国家重点实验室，博士后

1、原子精细发光团簇制备及应用
2、生物分析化学

3、细胞膜成像分析

上海市青年科技启明星项目（2021-2024）

上海市科技创新行动（2019-2022）

国家自然科学青年基金（2019-2022）

主持中国博士后基金（I类）（2016-2018）

广东省自然科学基金博士启动项目（2017-2020）

广东省自然科学基金-自由探索项目（2018-2021）

2024年

27. Chengpin Liang, Qiuling Huang, Haoran Zheng, Mulin Duan, Xinyi Cheng, Jielin Chen, Qian Li, Zhiyun Zhang*, Chunhai Fan, He Tian, Jianlei Shen*.

Probing Cell Membrane Tension Using DNA Framework-Encoded Vibration-Induced Emission Molecular Assemblies.J. Am. Chem. Soc. 2024, 146, 50, 34341–34351.

26. Cong Li,#, Xiaodong Xie,#, Mingqiang Li, Haozhi Wang, Xinyi Cheng, Jichao Zhang, Qian Li, Jiang Li, Xiaolei Zuo, Chunhai Fan*, J. Shen*.Ultrafast super-resolution imaging exploiting spontaneous blinking of static excimer aggregates. J. Am. Chem. Soc. 2024, 146, 28, 18948–18957.

25. H. Zheng, Y. Zhou, B. Yan, G. Zhou, X. Cheng, S. Lin, M. Duan, J. Li, L. Wang, C. Fan, J. Chen*, and J. Shen*. DNA Framework-Guided Self-Limiting Aggregation for Highly Luminescent Metal Cluster Nanoaggregates. J. Am. Chem. Soc. 2024, 146, 25, 17094–17102.

24. C. Li, J. Chen, T. Man, B. Chen, J. Li, Q. Li, X. Yang, Y. Wan*, C. Fan, J. Shen*.; DNA framework-engineered assembly of cyanine dyes for structural identification of nucleic acids. JACS Au 2024, 4, 3, 1125–1133.

2023年

23. Chen J#, Gu P#, Ran G#, Zhang Y#, Li M, Chen B, Lu H, Han Y, Zhang W, Tang Z, Yan Q, Sun R, Fu X, Chen G, Shi Z, Wang S, Liu X, Li J, Wang L,Zhu Y*, Shen J*, Tang B. Z.*, Fan C.*. Atomically precise photothermal nanomachines.  Nature Materials, 2024, 23, 271–280.

Nature Materials期刊 News and Views 发表题为"Molecular motion cools off gold nanoclusters" 报道。

22. Li, Y.#; Zheng, H.#;  Lu, H.#; Duan, M.; Li, C.; Li, M.; Li, J.; Wang, L.; Li, Q.; Chen, J.*; Shen, J.*; Noncanonical Condensation of Nucleic Acid Chains by Hydrophobic Gold Nanocrystals. JACS Au. 2023. 3, 8, 2206–2215.

21. Zheng, H.#; Li, H.#; Li, M.#; Zhai, T.; Xie, X.; Li, C.; Jing, X.; Liang, C.; Li, Q.; Zuo, X.; Li, J.; Fan, J.*; Shen, J.*;  Peng, X.; Fan C.; A Membrane Tension-Responsive Mechanosensitive DNA Nanomachine. Angewandte Chemie-International Edition 2023. 62,  e202305896.

2022年

20. Zhai, T.#; Zheng, H.#; Fang, W.#; Gao, Z.; Song, S.; Zuo, X.; Li, Q.; Wang, L.; Li, J.; Shi, J.; Liu, X.; Tian, Y.; Shen, J.*; Fan, C., DNA-Encoded Gold-Gold Wettability for Programmable Plasmonic Engineering. Angewandte Chemie-International Edition 2022. Doi: 10.1002/anie.202210377.

19. Liang, C.; Chen, J.; Li, M.; Ge, Z.; Fan, C.*; Shen, J.*, Probing the self-assembly process of amphiphilic tetrahedral DNA frameworks. Chemical Communications 2022, 58 (60), 8352-8355.

18. Liang, C.; Chen, J.; Li, M.; Li, Q.; Fan, C.*; Luo, S.*; Shen, J.*, Programming the self-assembly of amphiphilic DNA frameworks for sequential boolean logic functions. Chemical Communications 2022, 58 (63), 8786-8789.

17. Li, Y.; Zhai, T.; Chen, J.; Shi, J.; Wang, L.; Shen, J.*; Liu, X.*, Water-Dispersible Gold Nanoclusters: Synthesis Strategies, Optical Properties, and Biological Applications. Chemistry-a European Journal 2022, 28 (10).

16. Li, Y.; Lu, H.; Qu, Z.; Li, M.; Zheng, H.; Gu, P.; Shi, J.; Li, J.; Li, Q.; Wang, L.; Chen, J.; Fan, C.; Shen, J.*, Phase transferring luminescent gold nanoclusters via single-stranded DNA. Science China-Chemistry 2022, 65 (6), 1212-1220.

15. Zhai, T.; Sun, C.; Ye, D.; Xia, K.; Liu, X.; Fan, C.; Li, Q.*; Shen, J.*, Electrochemically driven assembly of framework nucleic acids. Journal of Electroanalytical Chemistry 2022, 905.

14. Feng, L.; Li, C.; Wang, L.; Li, J.; Liu, X.; Li, Q.; Luo, S.*; Shen, J.*, Self-Referenced Surface-Enhanced Raman Scattering Nanosubstrate for the Quantitative Detection of Neurotransmitters. ACS Applied Bio Materials 2022, 5 (5), 2403-2410.

13. Shen, J.; Situ, B.; Du, X.; Wang, Z.; Hu, R.; Li, B.; Qin, A.; Tang, B. Z., Aggregation-Induced Emission Luminogen-Based Dual-Mode Enzyme-Linked Immunosorbent Assay for Ultrasensitive Detection of Cancer Biomarkers in a Broad Concentration Range. ACS Sensors 2022, 7 (3), 766-774.

2021年

12.  Chen, B.; Huang, Q.; Qu, Z.; Li, C.; Li, Q.; Shi, J.; Fan, C.; Wang, L.; Zuo, X.; Shen, J.*; Li, J.*, Probing Transient DNA Conformation Changes with an Intercalative Fluorescent Excimer. Angewandte Chemie-International Edition 2021, 60 (12), 6624-6630.

11.Feng, L.; Li, J.; Sun, J.; Wang, L.; Fan, C.; Shen, J.*, Recent Advances of DNA Nanostructure-Based Cell Membrane Engineering. Advanced Healthcare Materials 2021, 10 (6).  

10.  Gu, P.; Chen, B.; Zhai, T.; Li, Q.; Zuo, X.; Wang, L.; Qin, A.; Zhou, Y.*; Shen, J.*, Immunostimulatory AIE Dots for Live-Cell Imaging and Drug Delivery. ACS Applied Materials & Interfaces 2021, 13 (17), 19660-19667.

9.  Yang, Y.; Chen, B.; Zhai, T; Feng, L.; Shen, J.*; Wang, L., Recent Progress of Aggregation-induced Emission Molecular Oligomers. Acta Polymerica Sinica 2021, 52 (9), 1100-1117.

2020年

8.   Xia, K.#; Shen, J.#; Li, Q.; Fan, C.; Gu, H., Near-Atomic Fabrication with Nucleic Acids. ACS Nano 2020, 14 (2), 1319-1337.

7. Shen, J.; Tao, K.; Gu, P.; Gui, C.; Wang, D.; Tan, Z.; Wang, L.; Wang, Z.; Qin, A.; Tang, B. Z.; Bao, S., Aggregation-induced emission luminogen for specific identification of malignant tumour in vivo. Science China-Chemistry 2020, 63 (3), 393-397.

6. Zhai, T.; Li, Q.; Shen, J.*; Li, J.; Fan, C., DNA nanostructure-encoded fluorescent barcodes. Aggregate 2020, 1 (1), 107-116.

5.   Zhang, Y.#; Shen, J.#; Hu, R.; Shi, X.; Hu, X.; He, B.; Qin, A.; Tang, B. Z., Fast surface immobilization of native proteins through catalyst-free amino-yne click bioconjugation. Chemical Science 2020, 11 (15), 3931-3935.

2019年

4.   Shen, J.#; Liang, L.#; Xiao, M.#; Xie, X.; Wang, F.; Li, Q.; Ge, Z.; Li, J.; Shi, J.; Wang, L.; Li, L.; Pei, H.; Fan, C., Fractal Nanoplasmonic Labels for Supermultiplex Imaging in Single Cells. JACS. 2019, 141 (30), 11938-11946.

3.   Xie, M.; Li, F.; Gu, P.; Wang, F.; Qu, Z.; Li, J.; Wang, L.; Zuo, X.; Zhang, X.*; Shen, J.*, Gold nanoflower-based surface-enhanced Raman probes for pH mapping of tumor cell microenviroment. Cell Proliferation 2019, 52 (4).

2.   Shen, J.; Jiang, X.; Xu, L.; Ge, Z.; Li, Q.; Song, B.; Wang, L.; Song, S., Poly-Adenine-Engineered Gold Nanogaps for SERS Nanostructures. ACS Applied Nano Materials 2019, 2 (6), 3501-3509.

1.   Shen, J.; Zhang, Y.; Hu, R.; Kwok, R. T. K.; Wang, Z.; Qin, A.; Tang, B. Z., Dual-Mode Ultrasensitive Detection of Nucleic Acids via an Aqueous "Seesaw" Strategy by Combining Aggregation-Induced Emission and Plasmonic Colorimetry. ACS Applied Nano Materials 2019, 2 (1), 163-169.

2018年前

7.   Shen, J.; Luan, B.; Pei, H.; Yang, Z.; Zuo, X.; Liu, G.; Shi, J.; Wang, L.; Zhou, R.; Cheng, W.; Fan, C., Humidity-Responsive Single-Nanoparticle-Layer Plasmonic Films. Advanced Materials 2017, 29 (35).

6.   Shen, J.; Tang, Q.#; Li, L.#; Li, J.; Zuo, X.; Qu, X.; Pei, H.; Wang, L.; Fan, C., Valence-Engineering of Quantum Dots Using Programmable DNA Scaffolds. Angewandte Chemie-International Edition 2017, 56 (50), 16077-16081.

5.    Shen, J.; Xu, L.; Wang, C.; Pei, H.; Tai, R.; Song, S.; Huang, Q.; Fan, C.; Chen, G., Dynamic and Quantitative Control of the DNA-Mediated Growth of Gold Plasmonic Nanostructures. Angewandte Chemie-International Edition 2014, 53 (32), 8338-8342.

4.    Hu, C.#; Shen, J.#; Yan, J.; Zhong, J.; Qin, W.; Liu, R.; Aldalbahi, A.; Zuo, X.; Song, S.; Fan, C.; He, D., Highly narrow nanogap-containing Au@Au core-shell SERS nanoparticles: size-dependent Raman enhancement and applications in cancer cell imaging. Nanoscale 2016, 8 (4), 2090-2096

3.     Shen, J.; Su, J.; Yan, J.; Zhao, B.; Wang, D.; Wang, S.; Li, K.; Liu, M.; He, Y.; Mathur, S.; Fan, C.; Song, S., Bimetallic nano-mushrooms with DNA-mediated interior nanogaps for high-efficiency SERS signal amplification. Nano Research 2015, 8 (3), 731-742.

2.     Shen, J.; Hu, R.; Zhou, T.; Wang, Z.; Zhang, Y.; Li, S.; Gui, C.; Jiang, M.; Qin, A.; Tang, B. Z., Fluorescent Sensor Array for Highly Efficient Microbial Lysate Identification through Competitive Interactions. ACS Sensors 2018, 3 (11), 2218-2222.

1.    Zhao, B.#; Shen, J.#; Chen, S.; Wang, D.; Li, F.; Mathur, S.; Song, S.; Fan, C., Gold nanostructures encoded by non-fluorescent small molecules in polyA-mediated nanogaps as universal SERS nanotags for recognizing various bioactive molecules. Chemical Science 2014, 5 (11), 4460-4466.

已授权国内发明专利：

1、一种形状可定制的框架核酸纳米发光体及其制备方法和应用，CN201910589495.9

2、一种荧光传感阵列对微生物进行分型鉴定的方法，CN201810783172.9

3、一种聚集诱导发光/表面等离子体色度分析双模式核酸检测方法，CN201810783689.8

4，一种用于生物分子固定的活化炔修饰表面玻璃材料及表面改性方法，CN201910309301.5

5，一种双模式ELISA酶免显色剂及其制备与应用，CN201811159246.8

上海市青年科技启明星（2021）

中国科学院大学院长奖（2016）

中国科学院大学优秀毕业生（2016）

长期欢迎具备原子精细团簇合成、超分辨成像背景、细胞膜化学研究背景的博士生及博士后加入！